Tomasz Osinski (Tomek)

Overview:

I am a bioinformatician making a bridge between people and computer hardware. I am interested in developing and applying my computer knowledge to make everyday computing easier for my collaborators. I have designed, built and currently maintain the computing system from CryoEM laboratory. Currently we have a little more than 2PB of storage and combined about 1000 CPUs, 6TB of RAM and 24 high-end GPUs, so that is a lot to take care of for one person. Currently part of the team developing Cryo-EM pipeline in the Center of Advanced Recearch Computing at the University of Southern California.

Center of Advanced Recearch Computing

Background?

I was studying bioinformatics at the Adam Mickiewicz University in Poznan, Poland under the supervision of Prof. Janusz Bujnicki. I did my PhD as a joined project between the University of Virginia and Adam Mickiewicz University. In Prof. Wladek Minor laboratory I have analyzed the surfaces of interfaces formed between allergens and antibodies. I gladly joined Ed Egelman’s lab and I want to use my skills to make science easier.

Janusz Bujnicki Laboratory website
Wladek Minor Laboratory website

Where do I see myself in 5 years?

Doing what I was doing all along - helping researchers get their work done.

For fun I like to:

- take photos
- hike
- travel

Publications with our group (see more on Google Scholar)

A Collagen Triple Helix without the Super Helical Twist. Mark A B Kreutzberger, Le Tracy Yu, Maria C Hancu, Michael D Purdy, Tomasz Osinski, Peter Kasson, Edward H Egelman, Jeffrey D Hartgerink Published in bioRxiv : the preprint server for biology, October 2024 (see publication)

Deterministic chaos in the self-assembly of β sheet nanotubes from an amphipathic oligopeptide. Fengbin Wang, Ordy Gnewou, Shengyuan Wang, Tomasz Osinski, Xiaobing Zuo, Edward H Egelman, Vincent P Conticello Published in Matter, October 2021 (see publication)

Structures of filamentous viruses infecting hyperthermophilic archaea explain DNA stabilization in extreme environments. Fengbin Wang, Diana P Baquero, Leticia C Beltran, Zhangli Su, Tomasz Osinski, Weili Zheng, David Prangishvili, Mart Krupovic, Edward H Egelman Published in Proceedings of the National Academy of Sciences of the United States of America, August 2020 (see publication)

Structure of a filamentous virus uncovers familial ties within the archaeal virosphere. Fengbin Wang, Diana P Baquero, Zhangli Su, Tomasz Osinski, David Prangishvili, Edward H Egelman, Mart Krupovic Published in Virus evolution, May 2020 (see publication)

A packing for A-form DNA in an icosahedral virus. Fengbin Wang, Ying Liu, Zhangli Su, Tomasz Osinski, Guilherme A P de Oliveira, James F Conway, Stefan Schouten, Mart Krupovic, David Prangishvili, Edward H Egelman Published in Proceedings of the National Academy of Sciences of the United States of America, October 2019 (see publication)

Ambidextrous helical nanotubes from self-assembly of designed helical hairpin motifs. Spencer A Hughes, Fengbin Wang, Shengyuan Wang, Mark A B Kreutzberger, Tomasz Osinski, Albina Orlova, Joseph S Wall, Xiaobing Zuo, Edward H Egelman, Vincent P Conticello Published in Proceedings of the National Academy of Sciences of the United States of America, July 2019 (see publication)

An extensively glycosylated archaeal pilus survives extreme conditions. Fengbin Wang, Virginija Cvirkaite-Krupovic, Mark A B Kreutzberger, Zhangli Su, Guilherme A P de Oliveira, Tomasz Osinski, Nicholas Sherman, Frank DiMaio, Joseph S Wall, David Prangishvili, Mart Krupovic, Edward H Egelman Published in Nature microbiology, May 2019 (see publication)

Structural conservation in a membrane-enveloped filamentous virus infecting a hyperthermophilic acidophile. Ying Liu, Tomasz Osinski, Fengbin Wang, Mart Krupovic, Stefan Schouten, Peter Kasson, David Prangishvili, Edward H Egelman Published in Nature communications, August 2018 (see publication)

Cryoelectron Microscopy Reconstructions of the Pseudomonas aeruginosa and Neisseria gonorrhoeae Type IV Pili at Sub-nanometer Resolution. Fengbin Wang, Mathieu Coureuil, Tomasz Osinski, Albina Orlova, Tuba Altindal, Gaël Gesbert, Xavier Nassif, Edward H Egelman, Lisa Craig Published in Structure (London, England : 1993), September 2017 (see publication)